It also has a high chance of scoring critical hits, offering a chance for scoring even more damage. But it has one downside: the use of Unload debuffs Lance's attack for a period of time, and this cannot be undone by using Purify, Medipack or the item Garlic. It is a good idea to buff Lance before hand with beer or Matt's "Temper", both of which buff attack.
However, since this debuffs only his physical attacks, such as his standard attack, his Snipe, Double Shot, and Unload itself, he can go on casting his spells (Plasma, Flamethrower, etc.) until the debuff wears off.